Predictive Genomics

Bundled deep within the nucleus of nearly every one of the 100 trillion cells that make up your body lies a unique and miraculous message. A message composed in the language of life itself— your DNA. Genes are Nature’s blueprint for "building" life. Genes are present in the central compartment (the nucleus) of almost every one of the 100 trillion cells in your body. In all, your body contains about 30,000-40,000 genes.

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At birth you inherit two set of genes—one set from each of your parents. Each gene contains a set of coded instructions that "explain" to your body how it will develop and function. Your height, your eye color, your voice, your hair texture—even certain elements of your "personality"—are strongly influenced by your genes.

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How do genes do this? Genes contain long double-stranded segments called DNA (deoxyribonucleic acid). DNA is formed by a sequence of four chemicals (called nucleotides). The arrangement of these four nucleotides makes up your genetic code. No two individuals (except identical twins) are born with the same exact arrangement. In fact, just by changing the order of these four chemicals, all the wondrous genetic diversity within the human race is created.

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Virtually all human diseases result from the interaction of genetic susceptibility and modifiable environmental factors, broadly defined to include infections, chemical, physical, nutritional and behavioral factors.

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Slight variations in genetic makeup called Single Nucleotide Polymorphisms ( SNPs – pronounced “ snips “ ) are associated with almost all diseases and can influence a person’s susceptibility to specific environmental factors that increase disease risk.

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Predictive Genomic can be applied to three broad areas of clinical relevance:

  • Predictive Genomic Testing – for more precise, proactive health risk screening.

  • Familial Association Testing – for identifying inherited risks within families.

  • Genomic Testing for Challenging/Refractory Cases – for chronic diseases that arise from multifactorial etiologies.

Through carefully targeted dietary, nutritional, lifestyle changes, as well as medicinal therapies, it is often possible to modify the expression of genes and to overcome the genetic limitations of biochemical pathways.

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